Factor X Deficiency

Hereditary factor X deficiency is a coagulation disorder with autosomal recessive inheritance. A genetic defect on chromosome 13 leads to a lack of factor X. Patients with mild disease may not have any symptoms but bleeding complications such as nosebleeds or bleeding into muscles and joints may occur in severe cases. Factor X deficiency may also be acquired as the result of liver disease, vitamin K deficiency or anticoagulants (blood thinners) such as warfarin.