Enzyme Deficiency Disorder
Effects of enzyme deficiency on the lungs
This disease is due to an inherited defect of an enzyme that protects the lungs from harmful substances during inflammatory reactions. People affected by this disease cannot produce enough of this enzyme or do not produce it correctly. As a result, the lungs of these patients are weakened and they have a higher risk of developing emphysema.
1 in 1,500 - 3,500
incidence of severe Alpha-1 in people of European origin
20 - 40 yrs. old
typical occurance of first signs and symptoms
estimated carriers of abnormal Alpha-1 genes in the United States